Multiparametric Flow Cytometry
Flow cytometry has revolutionized our ability to monitor immune responses by enabling the simultaneous tracking of a variety of cell surface and intracellular markers in many cell subsets and matrices in a sensitive and reproducible manner. It's a powerful single cell technology which enumerates rare cellular subsets and analyzes the relative distribution of phenotypic and functional subsets.
ImmuneCarta offers multiparametric flow cytometry that can be performed in many matrices including: whole blood, primary cells, fresh or frozen PBMC (peripheral blood mononuclear cells), cell lines, and Tumor-Infiltrating Lymphocytes (TILs).
Benefits and Applications
ImmuneCarta’s single-cell multidimensional assays allow for the identification of immunological signatures of protection, disease progression and/or therapeutic efficacy.
- Pharmacodynamic biomarkers
- Mobilization and enumeration of hematopoietic stem cells
- Kinase phosphorylation
- Signatures of polyfunctionality
- Intracellular cytokine secretion
- Phenotypic signatures of immune exhaustion
- Co-expression of co-inhibitory molecules
ImmuneCarta couples the expertise of our scientists with advanced multiparametric flow cytometry instrumentation.